DICL_CP_0308002 - DICL Database

Basic Molecular Information

Basic Information

DICL ID

DICL_CP_0308002

PubChem CID

10836

Molecular Formula

C₁₀H₁₅N

Molecular Weight

149.237 g/mol

Synonyms/Alias

[METHAMPHETAMINE; Metamfetamine; d-Deoxyephedrine; d-Desoxyephedrine; d-Methamphetamine; Methylamphetamine; d-N-Methylamphetamine; Metamphetamine; d-Methylamphetamine; N-Methylamphetamine; d-Phenyliso...[METHAMPHETAMINE; Metamfetamine; d-Deoxyephedrine; d-Desoxyephedrine; d-Methamphetamine; Methylamphetamine; d-N-Methylamphetamine; Metamphetamine; d-Methylamphetamine; N-Methylamphetamine; d-Phenylisopropylmethylamine; (S)-Methamphetamine; D-1-Phenyl-2-methylaminopropane; Norodin; (S)-Methylamphetamine; (+)-Methylamphetamine; d-(S)-Methamphetamine; Metamfetamina; Metamfetaminum; Methyl-beta-phenylisopropylamine; (+)-N-Methylamphetamine; 537-46-2; (+)-(S)-Deoxyephedrine; (S)-(+)-Deoxyephedrine; 1-Phenyl-2-methylaminopropane; Metanfetamina; Desyphed; S-(+)-Methamphetamine; (2S)-N-methyl-1-phenylpropan-2-amine; (+)-methamphetamine; (S)-N;alpha-Dimethylbenzeneethanamine; D-N;alpha-dimethylphenethylamine; Crank; Methamphetaminum; Meth; Crystal Meth; Metamfetamine [INN]; (+)-2-(N-Methylamino)-1-phenylpropane; Metamfetaminum [INN-Latin]; Metamfetamina [INN-Spanish]; Metanfetamina [INN-Spanish]; Methamphetaminum [INN-Latin]; (+)-N;alpha-Dimethylphenethylamine; dextromethamphetamine; D-1-Phenyl-2-methylaminopropan; (+)-N;alpha-Dimethyl-beta-phenylethylamine; Meth (Street Name); N-Methyl-beta-phenylisopropylamine; 1-Phenyl-2-methylamino-propan [German]; (+)-(S)-N-alpha-Dimethylphenethylamine; Metamfetaminum [Latin]; d-1-Phenyl-2-methylaminopropan [German]; 2S-(+)-Methamphetamine; (S)-(+)-Methamphetamine; (alphaS)-N;alpha-dimethylbenzeneethanamine; ICE [Street Name]; N-Methyl-beta-phenylisopropylamin [German]; Crank [Street Name]; Speed [Street Name]; NSC 25115; CHEBI:6809; HSDB 3359; (s)-phenylmethylaminopropane; EINECS 208-668-7; Crystal Meth [Street Name]; NSC-25115; (S)-N;alpha-Dimethylbenzeneethanoamine; UNII-44RAL3456C; (S)-(+)-N;alpha;dimethylphenethylamine; Metamfetamine (INN); Phenethylamine; N;alpha-dimethyl-; (+)-; 44RAL3456C; Benzeneethanamine; N;alpha-dimethyl-; (S)-; Methyl-.beta.-phenylisopropylamine; d-N;.alpha.-Dimethylphenethylamine; Stimulex; Speed; Benzeneethanamine; N;alpha-dimethyl-; (alphaS)-; J6.362B; DTXSID8037128; Desoxyephedrine hydrochloride; 1-Phenyl-2-methylamino-propan; Crank (Street Name); ICE (Street Name); Speed (Street Name); N-Methyl-beta-phenylisopropylamin; Metamfetaminum (Latin); Methamphetaminum [JP]; Metanfetamina [Spanish]; Metamfetaminum (INN-Latin); Crystal Meth (Street Name); Metamfetamina (INN-Spanish); Metanfetamina (INN-Spanish); Methamphetaminum (INN-Latin); N Methylamphetamine; N-Methyl-1-phenyl-2-propanamine; (+ )-Methylamphetamine; Benzeneethanamine; N;alpha-dimethyl-; (+)-; DEA No. 1105; B40; metamfetamine racemate; Methamphetamine (MA); Benzeneethanamine; N;.alpha.-dimethyl-; (S)-; Phenethylamine; N;.alpha.-dimethyl-; (S)-(+)-; Epitope ID:178090; intra-venous methamphetamine; Phenethylamine; N;alpha-dimethyl-; (S)-(+)-; Benzeneethanamine;.alpha.-dimethyl-; (S)-; d-N;a-dimethylphenethylamine; METHAMPHETAMINE [MI]; SCHEMBL42615; Phenethylamine;.alpha.-dimethyl-; (S)-(+)-; METHAMPHETAMINE [HSDB]; METAMFETAMINE [WHO-DD]; METHAMPHETAMINE [VANDF]; CHEMBL1201201; DTXCID6017128; WLN: 1MY1&1R -D; N06BA03; N;I+/--Dimethyl-phenethyl amine; Desyphed hydrochloride (Salt/Mix); NSC25115; N-Methyl-1-phenyl-2-propanamine #; BDBM50359499; PDSP1_001404; PDSP1_001405; PDSP2_001388; PDSP2_001389; (+)-N;.alpha.-Dimethylphenethylamine; (S)-N-methyl-1-phenylpropan-2-amine; DB01577; Desoxyephedrine hydrochloride (Salt/Mix); methyl[(2S)-1-phenylpropan-2-yl]amine; Phenethylamine;.alpha.-dimethyl-; (+)-; (+)-(S)-N-.alpha.-Dimethylphenethylamine; Benzeneethanamine;.alpha.-dimethyl-; (+)-; NS00000412; Phenethylamine; N;.alpha.-dimethyl-; (+)-; Benzeneethanamine; N;.alpha.-dimethyl-; (+)-; C07164; D08187; (+)-N;.alpha.-Dimethyl-.beta.-phenylethylamine; Q191924; Phenethylamine; N;alpha-dimethyl-; (S)-(+)- (8CI); Benzeneethanamine; N;alpha-dimethyl-; (alphaS)- (9CI); (+)-N;.alpha.-Dimethylphenethylamine hydrochloride (Salt/Mix)]

InChI Key

MYWUZJCMWCOHBA-VIFPVBQESA-N

InChI

InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1

IUPAC Name

(2S)-N-methyl-1-phenylpropan-2-amine

CAS Number

N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation

2D Molecular Drawing

Carbon (C)

Hydrogen (H)

Oxygen (O)

Nitrogen (N)

Sulfur (S)

SDF

11 11 0 0 0 0 0 0 0 0999 V2000
-3.3385 -1.2838 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.0218 -0.5652 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.7411 -1...

Download SDF File (1018 bytes)

Experimental Data

Activity Data

Target Ion Channel

Calcium-activated potassium channel subunit alpha-1

Uniprot Accession Number

Q12791

Function

Agonist

Species

Homo sapiens (Human)

IC₅₀

N/A (Not available)

EC₅₀

EC₅₀: 146000 nM

K_i

N/A (Not available)

K_d

N/A (Not available)

Inhibition

N/A (Not available)

Experimental Conditions

pH 7.4

Holding Potential

−50 to 120 mV mV

Temperature

25 °C

Test Method

Patch-clamping

Test Species

NG-108-15 cell

Binding Information

Binding Site

Not specified

Binding Site Residue

Not specified

Disease Information

Related Disease

Not specified

References

DOI

10.1016/j.toxlet.2013.08.021

URL

N/A (Not available)

PMID

24012886

Patent

N/A (Not available)

Computed Properties

Heavy Atom Count

Rotatable Bonds

logP

1.837

Complexity

48.6677

TPSA (Å²)

12.03

H-Bond Donors

H-Bond Acceptors

Ring Count

New Search

Molecular Details

Basic Molecular Information

Basic Information

Structure Information

Chemical Structure Visualization

Experimental Data

Activity Data

Experimental Conditions

Binding Information

Disease Information

References

Computed Properties